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(CNN) — The US Centers for Disease Control and Prevention on Friday released a highly anticipated update to travel guidance for people who are fully vaccinated against Covid-19, eliminating some testing and quarantine recommendations.

The CDC says that fully vaccinated people can travel at low risk to themselves.

The agency said that as long as coronavirus precautions are taken, including mask-wearing, fully vaccinated people can travel within the United States without getting tested for Covid-19 before or self-quarantining after.

For international travel, fully vaccinated people don’t need a Covid-19 test prior to travel — unless it is required by the destination — and do not need to self-quarantine after returning to the United States. They should still have a negative Covid-19 test before boarding a flight to the US, and a follow-up test three to five days after their return, the CDC noted.

The CDC considers someone fully vaccinated two weeks after receiving the last required dose of the Covid-19 vaccine. The updated guidance does not apply to unvaccinated people. The CDC advises anyone who hasn’t been fully vaccinated to continue to avoid travel.

Unvaccinated people who must travel should get tested one to three days before travel and again three to five days after travel. They should self-quarantine at home for seven days after travel, or 10 days, if they do not get tested post-travel.

The CDC said all Americans, regardless of vaccination status, should wear a mask and practice public health measures when traveling, such as physical distancing and washing hands frequently.

“With millions of Americans getting vaccinated every day, it is important to update the public on the latest science about what fully vaccinated people can do safely, now including guidance on safe travel,” CDC Director Dr. Rochelle Walensky said in a statement. “We continue to encourage every American to get vaccinated as soon as it’s their turn, so we can begin to safely take steps back to our everyday lives. Vaccines can help us return to the things we love about life, so we encourage every American to get vaccinated as soon as they have the opportunity.”

Last month, the CDC released its first iteration of guidance for fully vaccinated Americans, in which the agency said they should avoid travel. Some critics at the time said the CDC’s stance on travel for fully vaccinated people was too rigid.

Walensky defended the agency’s initial travel guidance at the time, explaining that changes to guidance would be ongoing as more people are vaccinated in the US and that scientific data would inform any recommendations.

“We are very worried about transmissible variants. A lot of them have come through our travel corridors, so we’re being extra cautious right now with travel,” Walensky told CNN’s Anderson Cooper in March. She noted that every time travel picks up, a surge in coronavirus cases follows, citing Independence Day, Labor Day and the holiday season.

Experts say that the US appears to be entering into another fresh surge this spring, which is partially due to more travel. The US averaged 63,974 daily cases over the last 7-days, up 11% since last week.